Mass Vaccinations Based on Great Marketing

If you have not been living off on some deserted land or cut off from civilization, you know about the COVID-19 pandemic. A cluster of cases of respiratory or gastrointestinal illnesses that was first reported in Wuhan, China in circa December, 2019 has spread to become global healthcare crisis. Most affected countries have initiated various public health policies after the respective countries declared infectious disease crisis due to putative etiologic agent called SARS-CoV-2 virus. This novel virus that is classified as human coronavirus is highly related to another coronavirus called SARS-CoV that was implicated to cause mini pandemic in 2002-2004 in China and elsewhere around the world. Of course, SARS-CoV did not cause the same level of morbidity and mortality that is SARS-CoV-2 (aka COVID-19) has been associated to cause in several classes of people around the world.

Most people infected with SARS-CoV-2 virus have recovery without developing severe symptoms or hospitalizations. People who have been infected with COVID-19 will have long-term or near lifetime immunity to novel SARS-CoV-2 or COVID-19 virus. Hence, even if they are infected by wild-type or even mutant SARS-CoV-2 virus, then their bodies will be able mount fast, robust immune response to re-infection since their immune system “remembers” prior infection with this class or type of virus. As you may know, there are hundreds of types of rhinoviruses, a class of virus that causes the common cold or upper respiratory infections (URIs). However, if you are infected with one type of rhinovirus (for example, R1) and recover from this cold, then any future infection from the same type of rhinovirus (R1) will not cause same illness or even very mild symptoms compared to the initial infection with that type of rhinovirus. Nonetheless, since there are hundreds of types of rhinoviruses, common cold or URIs by another type of rhinovirus (say R2, R3, R4…R95, etc.) can still cause infection since this rhinovirus type is different than R1 rhinovirus type. The immune system has not encounter this new type rhinovirus before, but can fight this virus by immune responses from innate and adaptive immunities to eliminate this new type of rhinovirus from the body and again remember this new type of virus to fight it again if reinfection occurs again. This dual between your body immune system and different kinds of viruses and moreover any pathogen that enters the body is always on 24-7 in human life provided one has healthy immune system.

Basically, the immune system has two major ways to fight pathogen or foreign agents that enter the body, one system is the innate immune response and other one is called the adaptive immune response. Without getting into the minutiae of the immune system, there are certain types of cells and tissues that make up the innate immune response. This system is found in mucosal tissues like respiratory tract, gastrointestinal tract, found in connective tissues of muscles, skin, brain, liver and other organs. On the other hand, adaptive immune response consists of white blood cells call lymphocytes that have ability to recognize, bind, trigger, and cause cascade of events that can result in destruction of any pathogen or foreign particles. The two primary lymphocytes called T-cells and B-cells constitute the cellular-mediated immunity conferred by adaptive immune response.

The beauty of the adaptive immune response is that any and different combinations of antigen or epitopes (short stretches of protein or amino acids and even carbohydrates or nucleic acids) can be recognized and activated by specific T-cells and B-cells (these cells make antibodies) to mount immune response to eliminate pathogens. The repertoire and subsequent refinement of activated or engaged T-cells and in particular B-cells is so vast that it has ability to adapt to slightly modified and even altered epitopes or antigens of same class of bio-molecules like proteins and trigger immune response to fight even altered or mutant (changed) pathogen since most key determinants on that pathogen are same or similar. Hence, the adaptive immune system allows the body not only to fight original pathogen, but it retains ability and can adapt to mount immune response to altered pathogen structures, too by recruiting other specific T- and B- cells that have inherent capacity to recognize such altered or mutated pathogens or bio-molecules located on that pathogen.

Now let’s look at the use of mass vaccination to confer immunity in general population in U.S.A. and around the world. The rollout of mass vaccination is not based on good and solid science, but relies on concerted efforts by governments (federal, state and local governmental bodies), big pharma, technology companies, mainstream media, and complicit medical or healthcare community to implement a mass experiment on human beings. In U.S.A., thus far, three vaccines for SARS-CoV-2 (COVID-19 virus) made by Pfizer-BioNTech, Moderna, and Johnson and Johnson have been approved by F.D.A. under Emergency Use Authorization (E.U.A.). These vaccines have not undergone rigorous and lengthy approval process for commercial grant of vaccine use in U.S.A. These vaccines supposedly were double-blind randomized clinical trials using vaccinated versus placebo (no vaccine or saline shot?). The safety and efficacy of these vaccines using clinical data endpoints are based on low clinical standards, namely, whether subjects experienced one or more cold or upper respiratory system or even GI symptoms like fever, headache, cough, body aches, diarrhea, etc. and/or having “positive” (+) rapid PCR test result. As previously presented here, rapid PCR test for COVID-19 yields high rate of “false” positive rates and has not been certified under any clinical standard for reference or as gold standard since the rapid PCR test has also been granted for diagnostic purpose under Emergency Use Authorization, too. The low bar set for clinical end points and not having sufficiently large number of participants deter us to know whether they prevent severe illness due to SARS-CoV-2 and/or hospitalizations. Also, to the best of present knowledge, the vaccine makers has not been published in any high-quality, peer-reviewed medical or scientific journal despite some data being available in F.D.A.’s regulatory repository.  The major pitfalls of these vaccines are:

1) As mentioned above, but it is worth repeating, F.D.A. has only granted  Emergency Use Authorization for emergency or experimental purpose and not usual formal approval for commercial use in U.S.A. Such similar processes (short cuts or on experimental basis approval) applies to vaccines made and being used in other countries around the world.

2) The newly-approved Johnson and Johnson vaccine, a one-shot vaccine that is stable at lower temperature and more hardy than Pfizer-BioNTech and Moderna’s vaccines is rifted with dubious ingredients. Johnson and Johnson vaccine is based on inserting SARS-CoV-2’s spike (S) protein in form of DNA (not mRNA unlike Pfizer-BioNTech and Moderna’s vaccines) into another viral vector called adenovirus (A26, a type of adenovirus). The fused DNA in adenovirus particles are injected into arms whereby, the viral vectors based on certain receptors on cells in muscle tissue will bind and enter into those cells. After entry, the these viral particles that contain S protein DNA complex enters cell’s nucleus and begins to produce many mRNA copies in nucleus that are transported into cell’s cytoplasm to make S proteins. These S proteins are then translocated to cell surface by binding to specific proteins on cell surface that can be recognized by local and migrating immune system to start local immune response. Most importantly, the adenovirus-mediated delivery system is cytotoxic and can cause cells that have uptaken these viral particles to break down and undergo process of cytolysis where internal and external parts of the cells are now present in the muscle tissue. The cytolysis process can also trigger local immune response and may cause auto-immune response to cellular compenents that are released in process of cytolysis.

3)There is no evidence that Johnson and Johnson vaccine confers systemic adaptive response since this data has not been published for review. Also, none of the three vaccines have been shown to activate and elicit innate immunity as presented above.

4) If a person has previously been infected with wild-type or original SARS-CoV-2 virus and fully recovered, they would have long-term innate and adaptive immunity to SARS-CoV-2 and even potential altered mutant viruses due built-in flexibility of the adaptive immunity. Hence, the recent news of “more contagious” SARS-CoV-2 variants from U.K. South Africa, Brazil, etc. would be recognized and robust immune response can be mounted by individuals who have been infected by native SARS-CoV-2 due to immunological memory and adaptive immunities. On the other hand, artificial immunity acquired by mass vaccination provides no guarantee that such immune response can fight variants since the immune response is limited to S protein on SARS-CoV-2. Conversely, the infection with SARS-CoV-2 and recovery elicits larger repertoire of adaptive immune response not only from S protein, but other proteins that encode structural and accessory proteins, too.

5) All three vaccines makers in U.S.A. enjoy “Immunity” against any claims or lawsuits alleging death, disability, long-term health consequences, defects, etc. arising out administering these vaccines into you! Moreover, healthcare providers, certain governmental units, and medical personnel have been conferred certain immunity protection in use of these Experimental Vaccines on the general population. The immunity protection were written by U.S. Congress under CARES and PREP Acts.  Interestingly , under United States Code, vaccine makers are given the Green Light to do administer any type of vaccines (tested or not fully tested)

42 U.S. Code § 300aa–22 – Standards of responsibility (b) Unavoidable adverse side effects; (1) “No vaccine manufacturer shall be liable in a civil action for damages arising from a vaccine-related injury or death associated with the administration of a vaccine after October 1, 1988, if the injury or death resulted from side effects that were unavoidable even though the vaccine was properly prepared and was accompanied by proper directions and warnings.”

(c) Direct warnings “No vaccine manufacturer shall be liable in a civil action for damages arising from a vaccine-related injury or death associated with the administration of a vaccine after October 1, 1988, solely due to the manufacturer’s failure to provide direct warnings to the injured party (or the injured party’s legal representative) of the potential dangers resulting from the administration of the vaccine manufactured by the manufacturer.”

See, how vaccine makers have no worries and do short cuts to get “shots in the arms” in administering vaccines to you without doing solid, high-quality science and publishing transparent clinical data!

SO THIS IS HOW THE DUMBING DOWN OF THE WORLD HAPPENS?!